Welcome to the centre for preimplantation genetic diagnosis


Preimplantation genetic diagnosis

We are based at Guy's Hospital. We are experts in the field of fertility and preimplantation genetic diagnosis (PGD).

Our aim is to provide you with information on what preimplantation genetic diagnosis is and how can it help you to achieve a pregnancy by avoiding the genetic condition known in your family.

We can offer PGD for:

  • tissue typing to provide a bone marrow matched sibling for a sick child (known as HLA typing)
  • fertilty preservation with PGD for those affected by an inherited form of cancer.

We are happy to consider PGD for other conditions not listed as it is usually possible to develop tests.

What is PGD?

Pre-implantation genetic diagnosis (PGD) is available to couples who are at risk of having a child with a specific genetic or chromosome disorder.

It involves the use of assisted reproductive technology (ART) which is also offered to couples with fertility problems, such as IVF and ICSI. The aim is to obtain and fertilise a number of eggs. Once fertilised, the embryos develop for five to six days  and then a number of cells are removed from each embryo that has formed a blastocyst (this is called trophectoderm biopsy). The genetic material (DNA) from the embryos is then tested for the genetic or chromosome abnormality. If unaffected embryos are available, usually one embryo is then transferred into the womb with the hope that it will implant and form a pregnancy. If successful, the baby should be unaffected by the disorder it was tested for.

Step 1 Create the embryos, followed by biopsy and testing. Freeze all tested embryos. Step 2 Transfer of unaffected frozen embryo


Contact us

Genetics enquiries and potential patients

Tel: 020 7188 1392
Email: pgdgenetics

Email: gst-tr.

Assisted Conception Unit (ACU) enquiries and current patients

Tel: 020 7188 2300
Email: IVF.PGD@

How do I get an appointment?

You need to be referred from a clinical geneticist. You must have already been seen in your local genetics department before attending our clinic.

Our team

Find out who you will meet when you come for your PGD appointment.


See our glossary of terms (PDF 11Kb) to explain any words you may not understand.


We can advise you about whether you are entitled to NHS funding.

If you are self funding, please email ivf.info@gstt.nhs.uk for our price list.

Find out more about our private PGD service