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Chest clinic
Room 4
2nd Floor, Southwark Wing
Guy's Hospital
Tel: 020 7188 5830
Download a map of Southwark Wing (PDF 39Kb)
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Thursdays, 9am-12 noon
Consultant allergist: Prof Chris Corrigan
Allergy nurse specialist: Keyna Bintcliffe
Omalizumab injection is used to treat moderate to severe persistent allergic asthma. It is used when a patient's asthma has not been controlled sufficiently on other asthma medicines.
Omalizumab is a medicine called an IgE blocker. IgE is short for immunoglobulin E. IgE is a substance that occurs naturally in the body in small amounts. This substance plays an important role in allergic asthma. When people with allergic asthma breathe in a year-round allergen, such as cat or dog dander, their bodies make more IgE. This may cause a series of reactions in your body that can lead to asthma attacks and symptoms. Omalizumab works by helping to block IgE.
The treatment involves one to four sub cut injections into the arm on a two-or four-weekly basis. The dosage and timing of the injections varies from person to person and is based on your weight and IgE blood levels.
During your first visit you will have to do a spirometry test, which is a breathing test to assess your lung function. This can be quite tiring for some individuals so we take our time to make sure we get good quality readings. A medical history is taken also to assess what triggers your asthma and what your coping mechanisms are.
We also measure your height and weight and take bloods.
You will then come back a week later for your first injection. It is important to note that after your first injection you will have to remain in the clinic for two hours. After that, the waiting period after your injections will only be 20 minutes.