Louise Coote Lupus Unit

Providing a highly specialist service for patients with lupus 

Our service

The Louise Coote Lupus Unit is the largest lupus unit in Europe. We provide a wide range of services for patients with lupus and other autoimmune connective tissue disorders and anti-phospholipid (Hughes) Syndrome.

In most hospitals lupus is part of the general rheumatology service. At Guy's and St Thomas' we are extremely fortunate in being able to provide patients and GPs with a distinct and highly specialist service.

We are at the forefront of research in lupus and autoimmune connective tissue disorders. Our lupus research unit is part of King's College London.

What is lupus?

Lupus is a disease in which the immune system becomes overactive. The normal immune system, which produces antibodies against foreign invaders, such as bacteria, goes into ‘overdrive’ and produces too many antibodies. It can affect any organ of the body.

It is often mistaken for other conditions, as the symptoms can be highly diverse, including:

  • fatigue
  • rashes
  • allergies
  • depression
  • kidney failure.

The cause is not known. There is a definite genetic tendency but despite years of research, no virus or infectious cause can be identified, neither is there evidence of an environmental cause.

All ages can be affected, but the commonest sufferers are young females, the peak ages being 18 - 45.

New nurse telephone clinic

The Louise Coote Lupus Unit is now offering a new online booking service for existing patients.

You can book an appointment online for a nurse to call you if you need advice or help with:

  • your diagnosis
  • medicines, including any side effects 
  • concerns about your symptoms that need to be addressed before your next appointment.



Tel: 020 7188 7600

Email: gst-tr.rheumandlupus

Did you know?

In 2014, the Louise Coote Lupus Unit was designated a LUPUS UK Centre of Excellence.