Debra Josephs


Consultant medical oncologist


Debra Josephs is a consultant medical oncologist at Guy's and St Thomas' NHS Foundation Trust. She completed her undergraduate medical degree at the University of Edinburgh, including a first class intercalated BSc.

She completed postgraduate training in London teaching hospitals, including the Royal Marsden Hospital, and completed her specialist medical oncology training at Guy's and St Thomas'.

In 2009 she was awarded a Cancer Research UK clinical research fellowship to complete a PhD in translational cancer immunology at King's College London. This led to her being awarded an academic clinical lectureship at Guy's and St Thomas' and King's College London to complete her clinical training, with a focus on clinical and translational research.

Debra became a consultant in urological and thoracic oncology at Guy's and St Thomas' in 2017. She specialises in the treatment of prostate, kidney, lung and thymic tumours, and is the joint lead clinician for prostate cancer. Debra is also an honorary senior lecturer at King's College London.

Education and training

  • Speciality certificate examination in medical oncology, Royal College of Physicians, 2015
  • Oncology MSc, The Institute of Cancer Research, 2015
  • PhD, King's College London, 2013
  • Membership of the Royal College of Physicians (MRCP), Royal College of Physicians, 2007
  • Bachelor of Medicine, Bachelor of Surgery (MBChB), University of Edinburgh, 2004
  • BSc (Hons) pharmacology, First Class, University of Edinburgh, 2003

Research interests

Debra's research interests include the development of novel therapies for cancer, with experience in both translational research and clinical trials.

Since 2018 she has been principal investigator of clinical trials in prostate and lung cancers, and she is senior principal investigator and co-lead of the PAIR study looking at the pathobiology of immune toxicities related to immune checkpoint inhibitor therapy.

Between 2017 and 2021 Debra was the clinical lead for cancer genomics for Viapath, leading on the effective delivery of molecular cancer diagnostics across south London. This developed her keen interest in understanding the genetics of urological and thoracic cancers, with a particular focus on prostate cancer.


  • BSc (Hons) pharmacology, prize for best research project, University of Edinburgh
  • McElwain Prize in medical oncology, Association of Cancer Physicians (national)
  • Sylvia Lawler Oncology Prize, Royal Society of Medicine (national)
  • Tim Plunkett Prize for excellence in oncology research (local)
  • Clinical Research Fellowship, Comprehensive Cancer Imaging Centre and Cancer Research UK
  • Prize for best poster discussion session, European Academy of Allergy and Clinical Immunology annual conference, Barcelona
  • Prize for best oral presentation, 'The tumour microenvironment: fundamental biology and translational research' conference, London, UK
  • Prize for best oral presentation, British Society for Investigative Dermatology annual conference, UK
  • Prize for best poster presentation, Comprehensive Cancer Imaging Centre biannual conference, UK
  • Starter grant for clinical lecturers, Academy of Medical Sciences

Last updated: May 2022

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