Gianluca Lucchese


Consultant cardiac surgeon


Gianluca Lucchese MD PhD was appointed consultant cardiac and mitral surgeon at St Thomas’ Hospital in 2016.

Before his recruitment to London, Gianluca had a comprehensive training in cardiac surgery in Italy and UK, including congenital cardiac, transplantation and mechanical circulatory support.

Over the last years he has focused on maximising his expertise on mitral and aortic valve repair surgery and complex aortic surgery with particular interest in the valve-sparing aortic root replacement. Also, he has pursued a specific interest in minimally invasive valvular surgery and trans-catheter valve implantation (such as TAVI), which have now become a consistent part of his surgical competences.

Research interests focus on the biochemical pathways of myocardial hypertrophy and myocardial protection, the hemodynamic properties of the aortic root (valve-sparing aortic root replacement, Ross operation) and the treatment of valvular heart disease with particular attention to the isolated tricuspid valve dysfunction.

Education and training

  • National Institute for Health Research – eLearning courses. Good Clinical Practice Certificate (primary care and secondary care) (London, 2015)
  • Workshop on cardiac intensive and critical care. Emogasanalysis and Ventilation Strategies in Difficult Scenarios (Milan, Italy, 2012)
  • EACTS meeting 2014 – postgraduate course: techniques of mitral valve repair (Milan, Italy, 2014)
  • PhD in cardiovascular sciences,  University of Verona, Italy (2012)
  • Italian Society of Cardiac Surgeons – postgraduate course (congenital): atrioventricular valves repair (Rome, Italy, 2012)
  • Training course on techniques of aortic valve repair (Homburg, Germany, 2012)
  • Medical Statistics II (Epidemiology) – University of Verona, Italy (2011)
  • Medical Statistics I – University of Verona, Italy (2011)
  • Training course on the HeartMate II® LVAD implant (Thoratec Italia), (Verona, Italy, 2010)
  • Workshop on congenital heart surgery – tailoring perfusion for the smallest (Munich, Germany, 2010)
  • Workshop on congenital heart surgery – pediatric ECMO (Geneva, Switzerland, 2010)
  • Graduated from the Medical School of Siena’s University (Italy) with honours (2002).

Research interests

  • Myocardial protection
  • heart remodelling
  • STAT proteins
  • Ross procedure
  • valve repair/replacement
  • medical statistic.


  • German Society for pediatric cardiology, 45th annual meeting (Weimar, 2013) – first prize for the research project entitled: “Early and late perspectives of the Ross (Ross/Konno) operation in the pediatric population: an Italian multi-centric study”
  • Department of cardiac surgery, University Hospital of Siena, Italy (2004) – first prize for the research project entitled: “Prophylaxis of post-operative AF with the combined use of sotalol and Mg+ in patients underwent isolated CABG” (author’s translation)
  • Medical School, University of Siena, Italy (1999) – first prize for the research project entitled: “New perspectives in the secondary prevention of the ischemic stroke” (author’s translation).

Last updated: April 2022

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