Jonathan Edgeworth

Jonathan Edgeworth is a man with short dark hair

Consultant microbiologist


Jonathan Edgeworth focusses on prevention, diagnosis and management of bacterial infections, particularly those due to antimicrobial resistant bacteria or that develop in patients while in hospital.

He works in both the diagnostic laboratory and on the wards providing an advisory service to clinicians to help them ensure their patients get appropriate antibiotic therapy, whilst limiting unnecessary antibiotic use that drives resistance.

Jonathan leads the clinical microbiology and infection consult service for critical care that includes a nationally commissioned extra-corporeal membrane oxygenation service.

He is also Director of  the Centre for Clinical Infection and Diagnostics Research (CIDR). The centre hosts academic clinicians, scientists, epidemiologists and research nurses focussed on epidemiology, surveillance and prevention of infections due to multi-drug resistant bacteria, development an evaluation of novel diagnostics, and clinical studies that improve the evidence base for effective use of antibiotics.

As Medical Director of Viapath Jonathan provide corporate medical leadership for pathology services provided to Guy’s and St Thomas’, King's College and Bedford Hospitals, with executive responsibility for Quality and Innovation. Further details can be found at

Jonathan has also been an active researcher for over 30 years. He started doing basic research to understand how bacteria cause disease and how we fight infection, but since joining the Trust in 2002 he has focussed on MRSA and more recently multi-drug resistant Gram negative bacteria (MDR-GNB) such as E. coli, Klebsiella and Pseudomonas.

Education and training

  • Undergraduate medical training – Kings College London and Addenbrooke’s Hospital Cambridge, 1983-1991
  • Intercalated PhD in Immunology – Cancer Research UK, 1986-1989
  • General medical and specialty training in clinical microbiology, 1991-1998
  • Wellcome Trust Clinical Fellowship – St George’s Hospital and Pasteur Institute, 1998-2002
  • MRCP, 1994
  • MSc Microbiology, 1998
  • FRCPath, 2006.

Research interests

The core objective of Jonathan's research is to provide information and evidence that helps clinical teams reduce antimicrobial resistance whilst also ensuring patients get the antibiotics they need.

The research includes:

  • understanding how resistant bacteria spread in the hospital and community
  • optimising screening and interventions to prevent spread
  • developing better diagnostics that can determine when patients do or do not need antibiotic
  • understanding how long to treat patients with antibiotics
  • understanding how the latest technological advances including bacterial genome sequencing can help identify and control bacteria that are more transmissible and virulent.

Last updated: April 2022

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