Melita Irving


Consultant clinical geneticist


Melita has been a consultant at Guy's and St Thomas' for fifteen years, during which time she has been deputy head of department, helped establish whole exome sequencing as a diagnostic genetic test and set up dedicated multidisciplinary clinics in skeletal dysplasia, achondroplasa-hypochondroplasia and dental genetics, including KBG syndrome.

She has local and regional clinics in general paediatric and adult genetic conditions, and in prenatal counselling.

As a key opinion leader and expert in clinical trials in rare diseases of the skeleton, Melita holds a number of national and international positions of responsibility.

She is also a clinical genetics academic training lead.

Education and training

  • Skeletal dysplasia fellowship - the Royal Children’s Hospital and Murdoch Children’s Research Institute, Melbourne, Australia (Oct 2006-07)
  • MD(Res) King’s College London – Clinical and molecular studies in skeletal dysplasia (June 2014)

  • FRCPCH March 2019

  • The Royal Society of Medicine (RSM) – president medical genetics section (Oct 2016-2019), chairman elect Ellison Cliffe Foundation (Dec 2018 -), trustee (Oct 2019-) and vice president (Feb 2020-).

Research interests

Melita's clinical service runs alongside her clinical research so her patients can benefit from pioneering trials for which she is chief/principal investigator:

  • Commercial - achondroplasia and multiple osteochondromas
  • Non-commercial - Schmid metaphyseal dysplasia
  • Preclinical studies - Hajdu-Cheney syndrome
  • DDD complementary analysis project – dental genetics
  • 100,000 Genomes – unexplained skeletal dysplasia GECIP


  • GSTT staff development fund (Oct 2006)
  • Travelling fellowship Ellison Cliffe Foundation (RSM) (Oct 2006-Oct 2007)
  • International Skeletal Dysplasia Society Maroteaux prize (June 2011)

Last updated: April 2022

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