Sheeba Irshad

Senior clinical lecturer


Sheeba Irshad is a senior clinical lecturer and breast cancer medical oncologist at Guy’s and St Thomas’ NHS Foundation Trust. Following her return from The Sidney Kimmel Comprehensive Cancer Center at John’s Hopkins University; she was appointed as a clinical deputy head of King’s College London Breast Cancer Now Research Unit Programme in 2018. She is also the deputy chair for NCRI’s for the Breast Cancer group.

As a CRUK-funded clinician scientist, she has established an independent research group focused on understanding the immune landscape of chemotherapy resistant breast cancers.

Research interests

The goal of Sheeba's research group is to find effective immunotherapy treatments for patients.

She is the translational lead and coordinating investigator for a multi-national clinical trial platform (PHOENIX) to explore the potential interactions between DNA damage response inhibitors and immunotherapy in high-risk Triple Negative Breast Cancers.

She is the chief investigator of a multi-centre “SOAP” study: Sars-Cov-2 for Cancer Patients. The research has directly contributed to changes in vaccine policy in the UK.

Additionally, she is the chief investigator for the “Outlier” study investigating the immune surveillance mechanisms in “exceptional responders” of stage 4 cancers.


  • CRUK Clinician Scientist Fellowship
  • ACP McElwain Award, NCRI conference, Liverpool, 2016
  • Tim Plukett Award. Guys and St Thomas’ Hospital Research Oncology 2016
  • ASCO Merit Award. American Society of Clinical Oncology conference, Chicago, USA, 2014
  • Susan G. Komen Breast Cancer Award. IMPAKT conference, Brussels, Belgium. 2013
  • Sarah Greene Clinical Fellowship Breakthrough Breast Cancer, London

Last updated: January 2023

Is this page useful?