Nicholas has built the Lane Fox Clinical Respiratory Physiology Research Centre, which hosts a programme of translational physiological research.
His research projects have received funding by the National Institute of Health Research, Medical Research Council, British Lung Foundation, Guy’s and St Thomas’ Charity, European Union and a number of industry partners.
He is currently primary supervisor to three King’s College London PhD students. Since 2009, he has successfully supervised two King’s College London PhD students (primary supervisor), one University College London PhD student (secondary supervisor) and one Oxford University MD student (secondary supervisor). One of the previous PhD students has received an NIHR Post-Doctoral Fellowship to continue her work in the Lane Fox Clinical Respiratory Physiology Centre.
Nicholas is currently Chief Investigator of five UKCRN NIHR portfolio trials and he has senior author peer-reviewed work published in the Journal of the American Medical Association, American Journal of Respiratory and Critical Care Medicine, Thorax, European Respiratory Journal, Chest, Critical Care Medicine, British Medical Journal Open, Cochrane Review, Journal of Physiology and Critical Care. He was awarded King's College London Readership status for Research and Clinical Excellence in Respiratory and Critical Care Medicine in 2013 and he was appointed as editor-in-chief of Thorax in 2015. Thorax is the 4th highest ranking respiratory journal in the world with an impact factor of 8.12.
Nicholas has developed a technology that has an intellectual property patent filing in the US and Europe and this has resulted with close collaborative industry links with Philips. He has a master research agreement with Philips to develop the Myotrace technology and he supervises a signal processing engineer working in the Lane Fox Clinical Respiratory Physiology Research Centre to commercialise the Myotrace technology. Nicholas was appointed to the Philips Global Executive Pulmonary Advisory Board in 2014 to identify and develop new technologies for respiratory health.