Pancreas transplant

Referrals

Making a referral

We accept referrals from other hospitals. Please email us to make a referral.

Before referring your patient, please make sure they have:

  • urea and electrolytes tests
  • estimated glomerular filtration rate (eGFR) 
  • calcium and phosphate tests
  • liver function tests
  • glycosylated haemoglobin (HbA1c) tests
  • a full blood count
  • a blood group test
  • a routine transplant assessment infection screen
  • an MRSA screen
  • urinalysis
  • chest X-ray
  • 12-lead electrocardiogram (ECG)
  • iliac artery and vein ultrasound 
  • echocardiogram
  • myocardial perfusion scan or dobutamine stress echocardiogram
  • ultrasound report of native kidneys (or an old non-functioning transplant)

Please include the test results in your referral letter.

Please email us for an up-to-date copy of our recipient work-up guidance document.  

Selection criteria

We accept patients if:

  • they have insulin-dependent diabetes mellitus (DM) and chronic renal failure and are already on dialysis or will be on dialysis within 6 months
  • an estimated glomerular filtration rate (eGFR) less than 20 mL/min/1.73 m2
  • they are under 65 years old (most patients are under 55 years old)
  • their body mass index (BMI) is less than 32 (most patients have a BMI of less than 30)
  • they have adequate cardiovascular reserve (this must be assessed by an echocardiogram and exercise tolerance test, or nuclear medicine myocardial perfusion scan or dobutamine stress echocardiogram)
  • they have adequate respiratory reserve and have been assessed by lung function tests if they are symptomatic or have a history of asthma or chronic obstructive pulmonary disease

We accept patients if:

  • they have insulin-dependent type 1 diabetes mellitus
  • they have life-threatening complications such as hypoglycaemic unawareness or "brittle diabetes" with frequent or severe episodes of hypoglycaemia
  • an estimated glomerular filtration rate (eGFR) more than 40 ml/min/1.73 m2
  • they have had a joint assessment with the diabetes team at King's College Hospital
  • their body mass index (BMI) is less than 32 (most patients have a BMI of less than 30)
  • they have adequate cardiovascular reserve (this must be assessed by an echocardiogram and exercise tolerance test, or nuclear medicine myocardial perfusion scan or dobutamine stress echocardiogram)
  • they have adequate respiratory reserve and have been assessed by lung function tests if they are symptomatic or have a history of asthma or chronic obstructive pulmonary disease

We accept patients if:

  • they have of insulin-dependent diabetes mellitus
  • they have stable function of a previous renal kidney transplant
  • an estimated glomerular filtration rate (eGFR) more than 40 ml/min/1.73 m2
  • their body mass index (BMI) is less than 32 (most patients have a BMI of less than 30)
  • they have adequate cardiovascular reserve (this must be assessed by an echocardiogram and exercise tolerance test, or nuclear medicine myocardial perfusion scan or dobutamine stress echocardiogram)
  • they have adequate respiratory reserve and have been assessed by lung function tests if they are symptomatic or have a history of asthma or chronic obstructive pulmonary disease

Exclusion criteria

We will not accept patients who have:

  • insufficient cardiovascular reserve, including the inability to climb a flight of stairs without stopping, a heart attack in the last 6 months, known uncorrectable significant coronary artery disease or poor heart function on testing
  • ongoing substance abuse
  • major psychiatric illness
  • immunosuppression likely to lead to life-threatening complications, such as active peptic ulcer disease or active sepsis
  • an 'incurable' cancer (excluding localised skin cancer)
  • a BMI more than 35

We may not accept patients who have:

  • extensive peripheral arterial disease
  • stroke with major functional impairment
  • significant history of non-compliance
  • significant history of alcohol or drug abuse
  • untreated hepatitis B, hepatitis C or HIV

Last updated: May 2023

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