What is a biobank?
Biobanking is when patients allow extra tissue that has been removed during an operation, biopsy or blood test to be collected or stored. This extra material, not needed for diagnosis or treatment, is analysed by scientists to find better ways to diagnose, prevent and treat conditions such as heart disease and cancer.
Human tissue donated for medical research can include:
- tissues/cells (cancerous and normal) from organs, bone marrow or blood
- other fluids from the body, such as urine.
Along with the extra tissue, the biobank also collects relevant information about each patient and their diagnosis.
Why are biobanks important?
Biobanks help scientists answer important questions about why conditions occur and who is at risk. The answers to these questions can lead to earlier, more accurate diagnosis and better treatment.
Biobanks and cancer
Within our cancer services, we have a well-established tradition of biobanking. We are licensed by the Human Tissue Authority to collect, store and provide samples to scientists researching the causes and treatments of cancer.
We want to enhance our resources to include different type of cancer. These are essential to understand what causes cancer and which treatment options are likely to be effective.
We aim to collect surplus tissue and blood samples from all patients who attend our hospitals and have a diagnosis or possible diagnosis of cancer.
If patients consent, samples including tumours and healthy tissue are collected. Data about the individual such as their family history, lifestyle and genetic make-up is also gathered and stored by the Biobank.
The samples and data can then be used for research studies aimed at improving the diagnosis and treatment of different cancers. More than 300 studies using Biobank resources have been published in scientific journals, including studies into the benefits of using genetic information to classify breast cancers.
Journey of a cancer biobank blood sample – video transcript
Text: The King’s Health Partners Cancer Biobank at Guy’s and St Thomas’ collects samples and medical information from patients with and without cancer to support vital research. We only do this with consent. This is what happens.
We discuss what happens when you give samples and data to the biobank and how this helps research.
You will be asked to sign a consent form.
We take a little extra blood when you have your routine tests.
Blood tubes are sent to the Biobank laboratory for processing.
Tubes are placed in a machine that spins them very fast so the blood divides into different parts.
Each one is carefully removed and separated into smaller tubes.
From each tube of blood donated, more than 16 small tubes are created.
Tubes are coded, so researchers are unable to identify you.
Tubes may be kept frozen, sometimes for several years, until needed by a researcher.
Samples can be used to support cancer research anywhere in the world.
Ask today about joining the King’s Health Partners Cancer Biobank at Guy’s and St Thomas’.