Genetic testing

We take blood tests to check the TP53 gene for mutations. The results may take up to 10 weeks. 

Extra genetic tests may be suggested for families based on their history of cancer. 

Results of genetic tests

Testing does not find a mutation in your TP53 gene

If this happens, the chance of a TP53 gene mutation being responsible for your history is small, but other genetic factors could be involved if you have a family history of cancer.

Testing finds an ‘unclassified variant’ in your TP53 gene

In about 1 in 20 (5%) cases, we find a genetic change (variant) in your TP53 gene but we do not know if this is significant. Future medical research may be able to tell us whether or not these variants relate to a family history of cancer.

We will not be able to use the test result to make decisions about cancer risk management for you or other family members.

Testing finds a gene mutation in your TP53 gene

This confirms an inherited increased risk of the specific types of cancer that the TP53 gene normally protects us from developing.