Oralvac Compact immunotherapy for allergies

This information should be read with the manufacturer’s leaflet that comes with your medicine. If you have any questions or concerns, speak to a doctor or nurse caring for you.

Oralvac® Compact is an unlicensed immunotherapy treatment for allergic reactions.

This treatment might be recommended for you if:

  • you have a severe allergy to house dust mites, tree pollen, or grass pollen
  • your current medicine does not control your symptoms very well

This treatment is given as drops that are put under your tongue (sublingual).

This medicine is not licensed for treating your health condition at this time. However, your doctor feels it is safe and effective treatment for you. Read more about unlicensed medicines.

How Oralvac Compact works

Oralvac Compact is used to treat the symptoms of an allergic reaction. Symptoms include:

These symptoms are caused by allergens. Almost anything can be an allergen, including pollen, animal fur, food and medicine. 

When you take Oralvac Compact drops, you take a small amount (dose) of the allergen that causes your reaction.

By taking many small doses you can build up a tolerance to the allergen you are affected by. This reduces the symptoms of your allergic reaction.

How to take Oralvac Compact

Take Oralvac Compact once a day, after a meal. 

  1. Pump the drops under your tongue. 
  2. Keep the medicine under your tongue for 1 to 2 minutes.
  3. After this time, swallow the medicine in your mouth. 

Your treatment will be in 2 stages:

  1. For the first week, you will take the maximum number of drops  
  2. After 1 week, the amount of drops you take each day is reduced. This is called the maintenance phase.

The full plan and length of your treatment will be explained to you by your doctor.

If you forget to take Oralvac Compact

If you forget to take Oralvac Compact for 1 day, you should take your usual dose as soon as you remember. 

If you have missed more than 1 day of your treatment, contact your medical team as soon as you can. 

Your medicine dose might need to be changed depending on how many treatments were missed, and what stage of treatment you are in.

Side effects of Oralvac Compact

You'll be taking a tree pollen, grass pollen or house dust mite allergen. This means you will have some of your normal allergy symptoms. For example, you might get a runny nose or watery eyes. 

These symptoms usually start immediately after you start Oralvac Compact. They should fade the longer you take the medicine. 

Please read the manufacturer’s leaflet for more information on side effects. 

You should contact a GP straight away if you have a severe allergic reaction. 

Oralvac and other medicines

You can take most other medicines with Oralvac Compact. This includes your usual treatment for hayfever or asthma. 

Tell your doctor about any medicines you are taking. This includes medicines prescribed for you and any medicines you buy (from a pharmacy or shop), such as vitamins, supplements and herbal or alternative medicines. 

Your doctor will check these medicines, to make sure they can be taken with Oralvac Compact. 

Talk to your doctor about any new medicines, before starting them. 

Tell any other doctor treating you that you are taking Oralvac Compact, and tell them before you have any medical or dental procedures. 

Vaccinations and Oralvac Compact

If you are having any vaccinations (such as the flu jab), you should not take Oralvac Compact on the day of your vaccine. 

If you have any reactions to a vaccination, you should wait until these have got better completely before restarting your Oralvac Compact. 

Pregnancy and Oralvac Compact

It's not known how Oralvac Compact affects an unborn baby, because there is limited data on its use during pregnancy. For this reason, it's not recommended for use during pregnancy. 

Contact your doctor if you become pregnant, or think that you might be pregnant during treatment. 

They will need to check your general health, and if Oralvac Compact has caused you any issues in the past. The doctor will recommend if you should, or should not, keep taking Oralvac Compact. 

Breastfeeding and Oralvac Compact

There's no information on if Oralvac Compact is found in breast milk or not. For this reason, it's recommended to not start treatment while breastfeeding. Please speak to your doctor for more information.

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Contact us

If you have any questions or concerns about drug allergy challenge testing, please contact the allergy nurse specialist.       

Phone: 020 7188 5830 Monday to Friday, 9am to 5pm.

Please call at least 5 working days before your appointment.

The messages are checked regularly, and your call will be returned as soon as possible. Please leave your name and phone number.

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