Genetic skin disease

We are a leading centre for diagnosing and treating genetic skin conditions.

We treat a wide variety of skin diseases, including:

  • ichthyosis
  • palmoplantar keratoderma (thickened skin on the palms of the hand and soles of the feet)
  • ectodermal dysplasia (a group of conditions affecting a combination of hair, nails, teeth or sweating)
  • pachyonychia congenita (a genetic skin condition causing thickened nails and skin problems)

Our department includes a diagnostic laboratory for:

  • analysis of skin biopsy specimens
  • genetic testing for rare genetic skin disorders

We hold clinics for:

We're involved in research to improve treatment and understanding of genetic skin conditions.

Health information

Changing Faces offers support to anyone with a scar, mark or condition on their face or body.

Ichthyosis support group offers support to people with ichthyosis.

Our consultants

Research and clinical trials

Research is vital to improving the care that you receive when you're unwell. You can help improve healthcare by taking part in research studies at our Trust. During your appointment, ask your healthcare professional about research. They'll be happy to tell you about research studies you could be eligible to join.

You can email [email protected] for more information.

Last updated: January 2024

Contact us

Phone: 020 7188 6399

Email: [email protected]

We aim to reply to emails within 2 working days.


Rare Diseases Centre, 1st floor, South Wing, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH

Dermatology department, ground floor, Bermondsey Wing, Guy's Hospital, Great Maze Pond, London SE1 9RT

Clinical help and advice

If you're an existing patient and need help or advice, please email our clinical nurse specialists (CNS).

Email: [email protected]

We aim to reply to emails within 2 working days.

Do you have any comments or concerns about your care?

Contact our Patient Advice and Liaison Service (PALS)

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