Having a bone biopsy

Bone biopsy in the interventional radiology department

A bone biopsy is a procedure done under X-ray or CT guidance. We remove a small sample of bone using a needle and send the sample to be tested in a laboratory.

Before your bone biopsy

Before your biopsy, we arrange for you to have some simple blood tests. The IR doctor needs to see a list of all your medicines. This includes any:

  • tablets
  • inhalers
  • creams
  • medicines that you buy in a pharmacy or shop, such as herbal remedies

Please bring a copy of your current prescription or a list of all your medicines to your pre-assessment appointment.

Sometimes, certain medicines need to be stopped before your procedure. This includes:

The IR doctor or nurse explains if you should stop any medicines and when you can start taking them again after your procedure.

If you need a hoist (piece of medical equipment to help lift or move you safely), transport or a translator, please contact the interventional radiology (IR) department.

On the day of the procedure

Here is some guidance about what to do on the day of your bone biopsy procedure:

Do

  • arrive 15 minutes before your appointment to allow enough time to prepare
  • change into a hospital gown
  • answer the IR doctor's questions when they check again which medicines you take
  • ask the IR doctor any questions that you would like before you sign the hospital consent form agreeing to have the procedure
  • ask 1 or 2 family members or friends to accompany you to the hospital and stay with you for 24 hours afterwards 
  • drink water until 2 hours before the procedure

Don't

  • do not eat or drink anything (except water) for 6 hours before the procedure

If you come to hospital with family or friends, we have limited space in the interventional radiology (IR) department. We may ask them to wait in the main X-ray reception.

We want to involve you in decisions about your care and treatment. If you decide to have a bone biopsy, we will ask you to sign a consent form. This says that you understand what is involved and agree to have the treatment.

You can read more about our consent process.

During the procedure

A bone biopsy is a quick procedure. The whole process takes about 30 to 45 minutes due to safety checks and preparation.

  1. A nurse takes you into the procedure room. At least 2 nurses and an IR doctor are with you at all times.
  2. You have a local anaesthetic medicine for the biopsy procedure. This means that you are awake, but we give you a medicine to make the area numb and free from pain. You should only feel the minimum amount of discomfort.
  3. Sometimes, we give you sedation medicine or stronger painkillers through a vein to make you sleepy (drowsy).
  4. The IR doctor positions you to make the biopsy as easy as possible.
  5. The nurses check your blood pressure and pulse throughout the procedure, and make sure that you are comfortable.
  6. The IR doctor uses an X-ray machine or CT scanner to help guide a special needle to the right place. This machine or scanner passes over you but does not touch you.
  7. We do the procedure through the skin and directly into the bone. The IR doctor takes a small sample of bone using the special needle.
  8. We send the sample of bone to be examined under a microscope in a laboratory.
  9. After the procedure, you have a small dressing over the area where we put in the needle. You do not need any stitches.

Resource number: 0245/VER5
Last reviewed: April 2024
Next review due: April 2027

A list of sources is available on request.

Trusted Information Creator. Patient Information Forum

Contact us

If you have any questions or concerns about a bone biopsy, please contact the interventional radiology (IR) department.

Phone:

We are open from Monday to Friday, 9am to 5pm.

If you need urgent medical attention, contact a GP, call 111 or go to your nearest emergency department (A&E).

Pharmacy medicines helpline

If you have any questions or concerns about your medicines, please speak to the staff caring for you.

You can also contact our pharmacy medicines helpline.

Phone: 020 7188 8748, Monday to Friday, 9am to 5pm

Email: [email protected]

We aim to respond to emails within 2 working days.

Do you have any comments or concerns about your care?

Contact our Patient Advice and Liaison Service (PALS)

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